在寄生虫线虫Haemonchus contortus的ACC-2受体上增加了CF3衍生levamisole的活性

Autumn Collins1, Sierra Varley1, Tobias Clark2

  • 1Applied Bioscience Graduate Program, Faculty of Science, University of Ontario Institute of Technology, 2000 Simcoe Street North, Oshawa, ON, L1G 0C5, Canada.

概括

研究人员开发了新的levamisole衍生品,针对寄生虫线虫类乙胆门化物通道 (ACCs). 化合物6是一种新的衍生物,对海蒙丘斯形虫ACC-2受体显著增强了敏感性,为新型杀虫剂药物提供了潜力.

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