在血管质量倡议数据库中验证WIfI分类
Dana Alameddine1, Keyuree Satam2, Martin D Slade3
1Division of Vascular Surgery and Endovascular Therapy, Yale University School of Medicine, New Haven, CT.
Journal of vascular surgery
|March 8, 2025
概括
伤口,缺血和足部感染 (WIfI) 分类准确地预测了血管质量倡议数据库中的慢性四肢威胁性缺血 (CLTI) 患者的重大截肢风险. 较高的WIfI阶段与截肢和死亡风险的增加有关.
科学领域:
- 血管外科 血管外科
- 临床结果研究研究
- 医疗信息学 医疗信息学
背景情况:
- 血管外科协会的伤口,缺血和足部感染 (WIfI) 分类是评估慢性四肢威胁性缺血症 (CLTI) 严重程度和预测截肢风险的验证工具.
- 血管质量倡议 (VQI) 外围血管干预 (PVI) 数据库收集了相关数据,但没有提供完整的WIfI分期.
研究的目的:
- 在VQI PVI数据库中验证WIfI分类.
- 分析不同WIfI组件组合在下肢再血管化 (LER) 后重大截肢的预测值.
主要方法:
- 对从2013年至2024年对患有CLTI的患者的VQI PVI数据的审查.
- 为符合条件的患者推导WIfI分数.
- 使用卡普兰-梅尔曲线和考克斯回归分析,比较不同WIfI阶段的患者特征和结果 (主要截肢,重新干预,死亡率).
主要成果:
- 对于42,858名患者,WIfI阶段导出是可能的,其中28,727人被纳入长期随访分析.
- 11.4%的患者经历了重大截肢;较高的WIfI阶段显著增加了1年的重大截肢或死亡风险 (阶段4:20.2%).
- WIfI临床阶段和末期病是主要截肢或死亡率的独立预测因素.
结论:
- 在VQI PVI数据库中验证了WIfI分类,证明了其在预测CLTI患者重大截肢和死亡率方面的实用性.
- 将WIfI分数整合到VQI模块中对于对外围动脉疾病的综合管理至关重要.
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