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Updated: May 6, 2026

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孕产妇败血症的全球发病率:一个系统性审查和元分析
1The Second District of the Department of Critical Care Medicine, Renai Hospital of Tianhe Guangzhou, Guangzhou, Guangdong 510000, China.
Journal of gynecology obstetrics and human reproduction
|March 8, 2025
概括
产妇败血症在全球每1万例怀孕中影响13.16例,区域差异很大. 关键的风险因素包括母亲的晚年,多胎妊娠和剖腹产,需要改善医疗干预措施.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 孕产妇败血症是一个关键的全球健康问题,也是孕产妇死亡的主要原因.
- 准确的发病数据和对风险因素的理解对于有效的预防和管理至关重要.
研究的目的:
- 系统地审查和元分析全球孕产妇败血症的发病率.
- 为了确定母体败血症发病率的区域差异.
- 检查与孕产妇败血症相关的危险因素.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在主要数据库 (PubMed/MEDLINE,Scopus,Google Scholar,EMBASE,Web of Science) 进行全面的文献搜索,截至2025年1月.
- 使用乔安娜·布里格斯研究所 (JBI) 工具和随机效应元分析进行严格的质量评估,以进行聚合发病率估计.
主要成果:
- 分析了44项涉及24个国家的超过1.41亿次怀孕的研究.
- 全球累计发生的孕产妇败血症估计在1万个怀孕中为13.16.
- 观察到显著的区域差异,非洲的发病率最高 (129.17/10,000),美洲的发病率最低 (6.31/10,000).
结论:
- 孕产妇败血症的发病率在全球范围内有所不同,累计发病率为1万例妊娠中13.16例.
- 确定的危险因素包括晚年孕产妇,多胎妊娠,子宫前,高血压,肥胖和剖腹产.
- 迫切需要加强医疗保健准入,改进数据收集和及时干预,以减轻世界各地的孕产妇败血症.
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