成人和儿童对多环芳的暴露:来自多个途径和来源的贡献
Namuun Batbaatar1, Xianqiang Fu1, Debra Bartelli1
1School of Public Health, University of Memphis, Memphis, TN, 38152, USA.
Environmental research
|March 8, 2025
概括
这项研究评估了土壤和空气中聚环芳 (PAH) 暴露的儿童和成人的健康风险. 车辆排放和煤炭燃烧是导致癌症风险的主要因素,为暴露控制策略提供了信息.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 环境化学环境化学
背景情况:
- 多环芳 (PAH) 是广泛存在的环境污染物.
- 有限的研究存在于多媒体PAH暴露的总体健康风险.
- 了解暴露途径和来源对于风险评估至关重要.
研究的目的:
- 估计来自土壤和空气的16种优先PAH的总剂量和癌症风险,用于儿童和成人.
- 识别和量化导致PAH暴露的来源.
- 为减轻与PAH相关风险的公共卫生战略提供信息.
主要方法:
- 在田纳西州孟菲斯收集了一年多的土壤和环境空气样本.
- 对环境介质中的16种优先PAH进行分析.
- 使用化学签名进行源分配.
- 平均每日剂量 (ADD) 和终身癌症风险的计算.
主要成果:
- 总PAH度 (ΣPAH) 在土壤中平均为7.6 mg/kg,在空气中平均为73.6 ng/m3.
- 吸入是儿童的主要暴露途径,而皮肤接触则在成人中占主导地位.
- 儿童的终身癌症风险估计为0.42 × 10−6,成人为0.55 × 10−6.
- 车辆排放,石油源和煤炭燃烧被确定为主要风险贡献者.
结论:
- 来自土壤和空气的PAHs的总体暴露带来了可量化的癌症风险.
- 儿童和成人之间的暴露路线和来源不同.
- 研究结果支持针对源控制和行为改变的有针对性的干预措施,以减少PAH暴露.
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