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Updated: May 23, 2025

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model
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糖分酶PKM2通过调节STAT3酸化来调节炎症性骨质结晶发生

Mingjuan Li1, Feng Li1, Chongjie Zhu1

  • 1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.

The Journal of biological chemistry
|March 8, 2025
PubMed
概括

酸激酶M2 (PKM2) 通过增强糖解和STAT3信号传递,驱动牙周炎的炎症性骨质细胞形成. 使用TEPP-46准PKM2可减少骨质损失,为牙周炎提供潜在的治疗方法.

关键词:
M2类型的酸激酶.葡萄糖溶解是什么这是一种炎症炎症炎症炎症.骨质细胞的骨质细胞.在p-STAT3中,牙周炎是指牙周炎的一种疾病.

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