先进的NLP驱动的预测建模,用于针对胃肠道癌症的量身定制治疗策略
Zhaojun Ye1, Haibin Ban1, Cuihua Li1
1Digestive System Department, Dunhuang Hospital, Dunhuang, Gansu,736200, China.
SLAS technology
|March 8, 2025
概括
本研究介绍了一种先进的自然语言处理 (NLP) 模型,用于个性化消化肠道癌症治疗. 该RAA-VLSTM模型使用电子健康记录准确预测治疗反应,改善个性化患者护理.
科学领域:
- 在瘤学瘤学.
- 计算生物学 计算生物学
- 医疗信息学 医疗信息学
背景情况:
- 胃肠道癌症是一个重大的健康挑战,需要个性化治疗策略.
- 目前的处理方法需要通过创新的数据驱动方法来增强.
研究的目的:
- 开发一种先进的自然语言处理 (NLP) 驱动的预测建模框架,用于个性化消化肠道癌症治疗.
- 为了利用深度学习和弹性亚当算法驱动的多功能长期短期记忆 (RAA-VLSTM) 模型来分析临床数据.
主要方法:
- 利用了广泛的电子健康记录 (EHR),包括人口统计数据,临床病史,治疗结果和遗传因素.
- 采用了NLP技术,包括令牌化,规范化,停止词删除和词嵌入用于特征提取.
- 实现了RAA-VLSTM模型,并优化了弹性Adam算法,以实现高效的训练和从顺序数据中特征学习.
主要成果:
- 该RAA-VLSTM模型表现出强大的预测能力,具有高性能指标:F1得分 (89.4%),准确性 (92.5%),回忆 (88.7%) 和精度 (90.1%).
- 该模型根据分析的临床数据准确预测了患者治疗反应和结果.
结论:
- 开发的NLP和机器学习框架显示了改善胃肠道癌症管理中的个性化护理的巨大潜力.
- 这项研究为未来的研究和先进的AI技术在瘤学的临床应用提供了坚实的基础.
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