基于介电分解的环境电离化质谱,辅助的是用纸包裹的棉巾
Yi-Ying Wu1, Chin-Pao Chiu1, Yu-Chie Chen2
1Department of Applied Chemistry, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan.
Analytica chimica acta
|March 8, 2025
概括
一种新的环境电离质谱法使用棉巾和片进行介电分解,使气相分析剂的简单有效的电离成为可能. 这种技术可以快速分析各种分析物,包括挥发性和低挥发性化合物.
科学领域:
- 分析化学 分析化学
- 质谱测量质量谱测量
背景情况:
- 环境电离质谱 (MS) 为分析原生环境中的样品提供了简单的方法.
- 使用电离空气分子进行介电分解电离是有前途的环境电离技术.
- 从水分子中产生质子,在介电分解中通过质子化启动分析物电离.
研究的目的:
- 探索使用包裹在片中的棉花棒作为环境电离的电离基质.
- 开发一种简单,有效和无设备的气相分析物电离方法.
- 通过使用MS与UV-Vis光谱学相结合,实现同时进行定性和定量分析.
主要方法:
- 在高电压 (-6000 V) 下,在质谱仪入口附近放置一个包裹在片中的棉巾.
- 这种设置诱导了空气分子的介电分解,产生了用于分析物电离的质子.
- 分析物的电离是通过挥发性和半挥发性物质的质子化实现的.
主要成果:
- 该方法成功通过质子化对分析物进行电离,酸的检测极限为18nM.
- 通过将MS与手持UV-Vis光谱仪相结合,实现了同时进行定性和定量分析.
- 该技术促进了对快速反应 (例如,伊米因形成) 的监测和对低挥发性分析剂 (例如,[a]pyrene) 的分析.
结论:
- 棉棒可以作为环境电离MS分析的直接电离基质.
- 这种方法简化了样本采集和分析,将采样探头集成到电离过程中.
- 该方法具有从各种样本矩阵中快速选目标分析物的潜力.
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