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Updated: May 23, 2025

Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells
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细菌细菌条件超变的突变景观显示了校对如何扭曲DNA聚合酶错误率

Ira Tanneur1,2, Etienne Dervyn1, Cyprien Guérin2

  • 1Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, 78350 Jouy-en-Josas, France.

Nucleic acids research
|March 8, 2025
PubMed
概括

DNA聚合酶错误和修复机制影响突变率. 这项在Bacillus subtilis中的研究揭示了校对可以防止不匹配的修复和,但可以放大聚合酶核酸选择性偏差.

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