相关实验视频

Updated: May 23, 2025

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

神经活动模式的时间和空间稳定性降低预测ADHD儿童的认知控制缺陷

Zhiyao Gao¹, Katherine Duberg², Stacie L Warren³

¹Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA. zygao@stanford.edu.

Nature communications

|March 8, 2025

概括

患有注意力缺陷/多动障碍 (ADHD) 的儿童在认知控制任务中表现出不稳定的神经活动,影响表现. 这种神经变异性与典型发育的儿童不同,突出显示了ADHD大脑功能的关键差异.

科学领域:

神经科学是一个神经科学.
认知心理学认知心理学
发展心理学发展心理学

背景情况:

注意缺陷/多动障碍 (ADHD) 与认知控制缺陷有关.
了解这些缺陷的神经基础,特别是试验水平的变化,至关重要.

研究的目的:

研究ADHD认知控制缺陷的神经基础.
检查在ADHD中主动和反应控制期间神经编码的试验级变异性.

主要方法:

使用了功能磁共振成像 (fMRI).
一个单一试验神经解码的计算方法被应用在一个有线索的停止信号任务上.
在双重控制模型中测试了主动和反应控制.

主要成果:

与典型发育 (TD) 儿童相比,ADHD儿童在主动和反应控制期间显示神经编码受损.
这种干扰的特点是,神经反应在突出和前端-双侧网络中的时间变化增加和空间稳定性降低.
在ADHD中神经变异与波动的任务性能和症状严重程度相关.
与TD儿童相比,ADHD在不同个体中表现出更多异质的神经反应模式.

结论:

在ADHD中观察到的认知控制缺陷中的一个重要因素是经过试验的神经变异性受损.
这些发现强调了在ADHD研究和临床理解中考虑神经编码变异性的重要性.

更多相关视频

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Published on: April 1, 2018

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

相关概念视频

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....

Information Processing Approach

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...