发育期暴露于空气污染会增加呼吸道过敏反应,改变转录组和DNA甲基化在女性成年后代

Razia Zakarya1,2, Yik Lung Chan3,4, Baoming Wang3,4

  • 1School of Life Sciences, University of Technology Sydney, Sydney, Australia. Razia.Zakarya@uts.edu.au.

PubMed
概括

母亲暴露于细颗粒物 (PM2.5) 空气污染对子女喘有表观遗传影响. 暴露母亲的后代表现出基因表达的减少和肺部DNA甲基化的改变,增加了喘的严重程度.

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