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Updated: May 23, 2025

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ABCC1变异对临床他类药物反应的结构和功能影响

Naomí Crispim Tropéia1, Paula Paccielli Freire1, Eduardo Willian de Alencar Pereira1

  • 1Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo, São Paulo, Brazil.

Journal of biomolecular structure & dynamics
|March 9, 2025
PubMed
概括

像ABCC1这样的ATP结合盒 (ABC) 载体中的遗传变异可能不会显著影响家族性高胆固醇血症患者的他类药物的疗效. 其他载体可能会补偿ABCC1突变,确保有效的药物去除.

关键词:
ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1ABCC1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1C1携带ATP结合的磁带传送器家庭性高胆固醇血症是什么?非同义词 (SNV) 误解变体

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