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周围脂肪和慢性病:系统性审查和元分析
Pengfei Kang1, Boju Sun2, Jing Hao1
1Department of Nephrology, First Medical Center of Chinese PLA General Hospital, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Military Logistics Research Key Laboratory of Field Disease Treatment, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.
Kidney & blood pressure research
|March 9, 2025
概括
周围脂肪的厚度与慢性病 (CKD) 有显著的关联. 这一发现凸显了考虑围脂肪作为CKD诊断和治疗的相关指标的重要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 医疗成像医学成像
- 公共卫生 公共卫生
背景情况:
- 之前的研究探讨了周围脂肪对慢性病 (CKD) 的影响.
- 然而,关于围脂肪与CKD相关性的系统审查和元分析缺乏.
- 这项研究解决了这一差距.
研究的目的:
- 系统地审查和对现有文献进行元分析.
- 调查周围脂肪和慢性病 (CKD) 之间的关联.
主要方法:
- 在六个主要的电子数据库 (PubMed,Scopus,Web of Science,Ovid,Embase,Cochrane Library) 进行了全面的搜索.
- 包括临床研究报告周围脂肪和CKD之间的关系到2024年9月10日.
- 使用Stata软件 (16 SE版本) 进行统计分析.
主要成果:
- 包含2576名患者的8篇文章被纳入了元分析.
- 在周围脂肪和CKD之间发现了显著的关联 (95%CI:0.48-0.65,p = 0.00).
- 没有发现显著的异质性 (I2 = 31.06%,p = 0.18),子组分析证实了糖尿病病,心脏功能障碍相关病和原发性CKD之间的关联.
结论:
- 周围脂肪的厚度与慢性病 (CKD) 密切相关.
- 临床医生在诊断和治疗CKD患者时应考虑围脂肪指标.
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