神经内分泌瘤不再是一种罕见的癌症吗?
Catherine Bouvier Ellis1, Nicola Jervis1
1Neuroendocrine Cancer UK, Warwickshire, UK.
Neuroendocrinology
|March 9, 2025
概括
罕见癌症的定义,如神经内分泌瘤 (NENs),需要修订. 目前的罕见癌症定义不准确地反映了真正的疾病负担,影响了NEN患者的医疗保健规划.
科学领域:
- 在瘤学瘤学.
- 癌症研究 癌症研究
- 流行病学 流行病学
背景情况:
- 神经内分泌新生瘤 (NENs) 是一个异质的瘤群,结果各不相同.
- 关于NEN分类,组成员身份以及在这种情况下"罕见"的定义,缺乏共识.
- 目前对罕见癌症的定义可能不准确地反映了NENs的患者群体和医疗保健需求.
研究的目的:
- 探索"罕见癌症"标签对神经内分泌瘤 (NENs) 的影响.
- 检查罕见癌症定义对认识,医疗保健和患者诊断的重要性.
- 评估当前罕见癌症定义是否充分代表疾病负担,并为NENs提供医疗保健规划信息.
主要方法:
- 这是一篇观点文章,并非基于经验数据.
- 它涉及对现有的罕见癌症定义及其对NENs的应用进行批判性审查.
- 分析如何在数据库和注册表中包含NEN子类型.
主要成果:
- 目前的罕见癌症定义,仅基于发病率,对于NENs来说是不够的.
- 在将NEN亚型纳入注册表中存在变化,突出了定义不一致性.
- "罕见"癌症标签可能不能完全为NEN患者提供适合疾病的医疗保健规划和提供信息.
结论:
- "罕见癌症"的定义需要对决策者解释和利用数据的方式进行修订或改变.
- 准确的定义对于有效的医疗保健政策,规划和为NEN患者提供服务至关重要.
- 解决定义不足对于满足NEN患者群体的医疗保健需求至关重要.
关键词:
意识 意识 意识 意识概念 概念 概念 概念达成共识 达成共识流行病学 流行病学事件发生率 事件发生率神经内分泌新生体的神经内分泌新生体.意见 意见 意见 意见流行程度 流行程度很少见的 很少见的更多相关视频
08:57Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
1.2K
12:13Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
Published on: November 19, 2019
6.7K
相关概念视频
01:21Smooth Endoplasmic Reticulum
5.6K
Smooth endoplasmic reticulum or smooth ER is a sub-organelle with specialized functions in animal cells and plant cells. It is often associated with the tubule morphology of the endoplasmic reticulum.
The ER provides optimal conditions for synthesizing steroid hormones and lipids, such as phospholipids and triglycerides. Traditionally, lipid metabolism was considered to be a smooth ER function. However, there is no direct evidence to prove that rough ER is completely excluded from lipid...
The ER provides optimal conditions for synthesizing steroid hormones and lipids, such as phospholipids and triglycerides. Traditionally, lipid metabolism was considered to be a smooth ER function. However, there is no direct evidence to prove that rough ER is completely excluded from lipid...
5.6K
02:23Abnormal Proliferation
4.4K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.4K
01:20The Retinoblastoma Gene
4.0K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.0K