大脑鼻静脉血栓的临床概况:印度南部的一项前性观察研究
Gowthaman Kasiviswanathan1, Sujatha Sivashanmugam2, Ramya Bakthavatchalam3
1Department of General Medicine, K.A.P. Viswanatham Government Medical College Hospital, Tiruchirapalli.
The Kurume medical journal
|March 9, 2025
概括
大脑鼻静脉血栓形成 (CSVT) 影响中年成人,经常出现头痛和发作. 早期诊断和管理导致这种静脉疾病的预后良好.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 放射学 放射学是一门学科.
背景情况:
- 大脑鼻静脉血栓形成 (CSVT) 涉及大脑静脉和鼻中的血块.
- CSVT表现出多样化的症状,这给诊断带来了挑战.
- 在农村人口中了解CSVT对于有效管理至关重要.
研究的目的:
- 调查CSVT的临床,放射学,病因学和结果方面.
- 在特定的农村人口群体中描述CSVT.
- 确定CSVT的风险因素和治疗结果.
主要方法:
- 包括怀疑CSVT和确认神经成像 (MRI/MRV) 的患者.
- 排除标准包括正常的神经成像和其他神经疾病.
- 实验室测试分析了凝血因子 (蛋白C,S,抗血栓III),自身免疫标记物 (ANA,APLA) 和同类半氨酸水平.
主要成果:
- 在21-40岁的年龄组中,CSVT的发病率达到峰值 (44.3%),主要在男性中.
- 亚急性呈现 (61.4%) 是常见的,头痛 (80%) 和作为主要症状.
- 最受影响的是上部斜侧鼻 (51.4%) 和横侧鼻 (25.7%);高homocysteinemia (40%) 和蛋白 C/S 缺乏 (14.3%) 是关键病因. 93%的人完全康复.
结论:
- CSVT主要影响中年成人,表现为头痛和发作.
- 过高homocysteinemia和蛋白质C/S缺乏是显著的贡献因素.
- 早期诊断和及时治疗与出色的患者结果有关.
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