顶牙周炎相关的根性囊流体中的细菌属:一项观察性研究
David Szaraz1,2, Jan Bohm3, Sabina Cerulova3
1Clinic of Maxillofacial Surgery, University Hospital Brno, Brno, Czech Republic.
International endodontic journal
|March 10, 2025
概括
对顶性牙周炎相关的根性囊的细菌分析显示,特定的无氧性,阴性细菌的多样性较低,但占主导地位. 大多数囊液不是无菌的,它们含有Prevotella,Fusobacterium和Porphyromonas.
科学领域:
- 微生物学 微生物学
- 口腔健康 口腔健康
- 传染性疾病 传染性疾病
背景情况:
- 顶部牙周炎 (AP) 可以导致根性囊 (RCs).
- 这些囊的微生物组成尚未完全理解.
研究的目的:
- 评估与AP相关的RCs流体中的细菌组概况 (细菌属的多样性,组成和相对丰度).
主要方法:
- 在29名AP和RC患者的观察性研究中.
- 采集的样本包括上斑,冷粉化牙和囊性液体.
- 使用16S rRNA amplicon测序进行细菌组分析.
主要成果:
- 在79%的病例中,囊性液体细菌组与负对照不同.
- 在囊性液体和牙中较低的α-多样性 (明显的安普利康序列变异和香农指数),与supragingival斑块相比.
- 在囊性液体中,厌氧性,グラム阴性属 (Prevotella,Fusobacterium,Porphyromonas,Fretibacterium) 的丰度增加.
结论:
- 大多数根性囊液不是无菌的,尽管其α多样性低于supragingival斑块.
- 特定的无氧性阴性细菌属主导着与AP相关的RCs的微生物景观.
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