在ACL重建后,四肢运动单元的特性与皮质脊髓刺激性和运动皮质激活有关
David A Sherman1,2, Jonathan P Beausejour3, Moein Koohestani3
1Physical Therapy, Movement, and Rehabilitation Sciences, Northeastern University, Boston, Massachusetts, United States.
Journal of applied physiology (Bethesda, Md. : 1985)
|March 10, 2025
概括
前十字带重建 (ACLR) 后的个体显示四头肌运动单元发射受损,大脑活动减少. 这表明,皮层驱动器的减少有助于术后持续的四头肌疲弱.
科学领域:
- 神经科学是一个神经科学.
- 康复科学 康复科学 康复科学
- 发动机控制器的控制器
背景情况:
- 在前十字带重建 (ACLR) 后,四头肌疲软是一个重要的问题.
- 神经成像显示ACLR患者的运动抑制和皮质脊髓管缩.
- 脊上机制可能是ACLR后的运动神经元损伤和弱点的基础.
研究的目的:
- 为了调查ACLR后的运动单元损伤和四头肌弱的脊柱上贡献.
- 在ACLR之后,探索巨型中枢肌肉中运动单元的发射模式.
主要方法:
- 高密度电肌图 (EMG) 用于分解巨大的中介体中的运动单元 (MU) 动作潜力.
- 电脑电图 (EEG) 用于定位皮层活动和跨磁刺激 (TMS) 用于皮层脊髓刺激.
- 在20名ACLR患者和20名对照人群中比较MU特性,皮质活动和皮质脊髓刺激性.
主要成果:
- ACLR参与者表现出较弱的四头骨,招募更大的MU,在涉及的肢体中射击速度较低.
- 在ACLR个体中观察到较低的皮质脊髓刺激性和减少的逆侧运动皮质激活.
- 在ACLR后的较低绝对和质量正常化值时,招募了更大,更慢的MU.
结论:
- 减少刺激性皮质驱动可能会导致ACLR后四头肌运动单元损伤.
- 运动单元招募障碍和较低的皮质脊髓刺激性与ACLR后持续的四头肌软弱有关.
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