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全国范围的估计,通过医院前输血挽救的潜在生命
Daniel T Lammers1,2, Richard Betzold3, Reynold Henry4
1University of North Carolina Medical Center, Chapel Hill, North Carolina, USA.
Transfusion
|March 10, 2025
概括
在全国范围内实施医院前血液制品 (pBP) 可以每年为创伤患者在出血休克中挽救数千人的生命. 这项研究估计,在2020-2023年期间,通过完全的pBP访问,有超过21000个潜在的生命被拯救.
科学领域:
- 紧急医疗 紧急医疗
- 创伤外科 手术 创伤外科
- 公共卫生政策 公共卫生政策
背景情况:
- 医院前输血显著降低了出血性休克的死亡率.
- 在美国,医院前血液制品 (pBP) 的全国实施有限.
- 关于广泛的PPB访问影响的数据很少.
研究的目的:
- 估计通过完全实施pBP来挽救受伤患者在出血性休克中的生命数量.
- 分析2020年至2023年之间的潜在影响.
主要方法:
- 对创伤患者≥16年NEMSIS数据 (2020-2023) 的回顾性审查.
- 纳入标准:低血压 (SBP<90 mmHg或<70 mmHg) 和心动减速 (HR>108 bpm) 没有pBP.
- 使用已公布的死亡率和风险比率 (RR) 估计来计算潜在的挽救生命.
主要成果:
- 260,472名患者符合纳入标准.
- 据估计,在四年内,可以预防21,356例死亡.
- 假设24小时死亡率为22.1%和RR为0.629.
结论:
- 广泛的医院前输血可以挽救数千人的生命.
- 需要进行政策干预,以增加PPB的采用和可用性.
- 建议立即努力,以提高获得救命的医院前干预措施的机会.
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