贝塞特病中腹功能障碍及其与疾病临床表现的关系:一个病例控制研究
Gizem Varkal1, Rabia Eker Akıllı2, İpek Türk1
1Department of Internal Medicine, Division of Rheumatology, Çukurova University Faculty of Medicine, Adana, Türkiye.
这里是Behçet.
科学领域:
- 心脏病学 心脏病学
- 类风湿病学 类风湿病学
- 内部医学 内部医学
背景情况:
- 贝切特病 (BD) 是一种多系统性炎症性疾病.
- 在BD中,心脏干扰,特别是腹筋功能障碍 (DD),可能会发生.
- 早期识别DD对于管理心脏并发症至关重要.
研究的目的:
- 为了确定患有贝塞特病 (BD) 的患者中腹功能障碍 (DD) 的患病率.
- 调查DD与BD患者临床表现之间的关联.
主要方法:
- 一项病例控制研究包括70名BD患者和50名健康对照.
- 胸外回声心脏成像用于测量E/A和E/E'比率,这是DD的标志物.
- 记录了临床数据,包括器官参与和疾病持续时间.
主要成果:
- 扩张性功能障碍在BD患者 (27.1%) 中的频率明显高于对照组 (8%) (p=0.017).
- 血管干扰与DD的更高患病率有关 (中枢E/A比率<1) (p=0.034).
- 患有DD的患者年龄较大,疾病持续时间较长,红细胞沉积率较高.
结论:
- 腹筋功能障碍是贝塞特病患者的常见发现.
- 在BD中,血管参与是发展扩张性功能障碍的危险因素.
- DD可能是BD中心脏参与的早期指标.
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