患有牛皮关节炎的患者的肺部参与
Mehmet Hünür1, Tahir Saygın Öğüt2, Ece Çelik3
1Department of Internal Medicine, Akdeniz University Faculty of Medicine, Antalya, Türkiye.
Archives of rheumatology
|March 10, 2025
概括
肺病变,包括间歇性肺病 (ILD),在10.1%的牛皮关节炎患者中被发现. ILD的患病率低于其他连接组织疾病,没有观察到角纤维化.
科学领域:
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
- 放射学 放射学是指放射学
背景情况:
- 牛皮关节炎 (PsA) 是一种慢性炎症性疾病,与各种关节外表现有关.
- 肺部参与PsA越来越被认可,但需要进一步的表征.
- 了解PsA中的肺病变模式对于全面的患者管理至关重要.
研究的目的:
- 为了确定患有牛皮关节炎的患者肺病变的患病率和病变模式.
- 识别特定类型的肺部异常,包括间歇性肺部疾病 (ILD) 和结节.
- 为了将PsA中的ILD频率与其他相关疾病进行比较.
主要方法:
- 根据CASPAR标准诊断的247名牛皮关节炎患者的回顾性审查.
- 2014年至2020年间肺部症状和胸部成像发现 (CT/HRCT) 的分析.
- 确定的肺病变和ILD亚型的分类.
主要成果:
- 在PSA患者中,肺病变在10.1%的患者中被发现.
- 间歇性肺病 (ILD) 发生在3.6%的队列中,非特异性间歇性肺炎是最常见的亚型.
- 肺结节 (8.5%) 和气道异常 (6.1%) 也经常被观察到. 在老年男性,吸烟者和服用氧化的人群中,ILD的发病率更高.
结论:
- 牛皮关节炎患者的ILD的患病率和严重程度与结缔组织疾病相比似乎较低.
- 状纤维化,在结性脊髓炎中观察到的一个特征,在这个PsA队列中显著缺席.
- 这些发现突出了PsA中特定的肺部参与模式,与其他脊髓关节病不同.
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