四种查工具的性能,用于在失眠患者中识别阻塞性睡眠呼吸暂停
Chuan Shi1, Yuxin Wang1, Jinmei Luo1
1Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science (CAMS) and Peking Union Medical College (PUMC), Beijing, 100730, People's Republic of China.
Nature and science of sleep
|March 10, 2025
概括
对于患有失眠的人来说,STOP-Bang问卷显示了对查阻塞性睡眠呼吸暂停 (OSA) 的高度敏感性. 这种工具被推用于准确的OSA检测在并发性失眠和OSA患者.
科学领域:
- 睡眠医学 睡眠医学
- 诊断工具 诊断工具
- 临床研究 临床研究
背景情况:
- 同病性失眠和阻塞性睡眠呼吸暂停 (OSA) 在临床环境中很普遍.
- 现有的OSA查工具在失眠人群中缺乏验证,由于白天功能评估,可能会影响准确性.
研究的目的:
- 为了验证四种常见的OSA查工具 (STOP-Bang,爱普沃思睡眠度量,柏林问卷,NoSAS) 在患有和没有失眠的个体中的性能.
- 评估失眠对这些查工具的诊断准确性的影响.
主要方法:
- 一项对1266名被怀疑患有OSA的参与者进行的横截面调查,他们正在接受睡眠研究.
- 参与者填写了失眠严重程度指数 (ISI),STOP-Bang,ESS,柏林和NoSAS问卷.
- 临床失眠被定义为ISI分数≥15.5的临床失眠. 使用灵敏度,特异性和ROC曲线来评估性能.
主要成果:
- 在存在失眠的情况下,STOP-Bang,ESS和柏林显示敏感性增加,但在检测OSA时特异性降低 (呼吸暂停-呼吸暂停指数≥15/h).
- 在传统的切断点上,STOP-Bang获得了最高的灵敏度 (93.2%),而NoSAS具有最高的特异性 (67.7%).
- 与ESS和柏林相比,STOP-Bang和NoSAS在所有OSA严重程度上表现优越 (ROC AUC>0.7).
结论:
- 失眠会改变评估白天功能的OSA查工具的性能.
- 在使用常规切断时,STOP-Bang被确定为首选的查工具,因为它在患有并发性失眠和OSA的患者中具有高灵敏度.
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