颗粒状水凝作为脆性产量应力流体
G B Thompson1,2, J Lee1, K M Kamani1
1Dept. Chemical and Biomolecular Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801.
bioRxiv : the preprint server for biology
|March 10, 2025
概括
颗粒状水凝表现出复杂的质学,表现为易碎的产量应力流体. 一个新的模型量化了它们的短暂行为,有助于合理设计3D生物打印等生物医学应用.
科学领域:
- 材料科学 材料科学 材料科学
- 类风病学 类风病学 类风病学
- 生物医学工程 生物医学工程
背景情况:
- 颗粒状水凝广泛用于生物医学应用.
- 目前的风湿学特征化方法通常集中在剪切稀释,自我愈合或整体指标上.
- 需要详细分析在屈服和坚定过程中的过渡性风湿性行为.
研究的目的:
- 开发和应用一个分析框架,以全面描述颗粒状水凝的质性行为.
- 研究微凝和颗粒状组合特性对稳定和短暂的类风病学的影响.
- 建立一个定量模型,用于合理设计颗粒状水凝.
主要方法:
- 使用振荡剪切测试与Kamani-Donley-Rogers (KDR) 模型相结合,结合性 (Bt).
- 通过变化的微凝组成和直径,颗粒包装和滴滴异质性量化定量的稳定和短暂的类风病.
- 分析了聚乙烯甘醇和凝微凝的混合物.
主要成果:
- 颗粒状水凝被描述为具有复杂的短暂质的脆性产量应力流体.
- 使用Bt的KDR模型在各种设计参数中有效捕捉了颗粒状水凝的行为.
- 风病行为和模型参数与单质和混合水凝中的微凝成分相关.
- 自愈行为被强烈捕获,并且发现颗粒性放松时间取决于应变幅度.
结论:
- 带有Bt的KDR模型为理解和预测颗粒状水凝类风病学提供了定量框架.
- 这种方法将复杂的过渡性风湿学减少到可管理的模型参数.
- 这些发现有助于合理设计颗粒状水凝,用于各种应用,包括注射, *in situ* 稳定和3D生物打印.
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