出生时社会感知途径中的功能连接性与4个月时对面部的注意力有关
bioRxiv : the preprint server for biology
|March 10, 2025
概括
在正确的社会路径中早期的功能连接与以后的社会关注有关. 这一发现对于理解自闭症和社会认知中的发育差异至关重要.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 社会认知是指社会认知.
背景情况:
- 右侧社会视觉感知通路,涉及中间/视觉5区 (MT/V5) 和上突 (STS),支持处理面部和语音.
- 对于这种社会途径的发展轨迹及其与长期社会结果的相关性,人们的理解有限.
- 本研究探讨了新生儿正确社会途径中的内在功能连接 (iFC) 以及它与社会注意力的预测关系.
研究的目的:
- 检查神经型新生儿在正确的社会途径中的内在功能连接 (iFC).
- 为了将这个iFC与左侧社会和双边背侧注意力通路的iFC进行比较.
- 探索新生儿iFC与神经多样性新生儿的社会关注之间的潜在联系.
主要方法:
- 本质功能连接 (iFC) 测量了来自人类连接组项目 (dHCP) 的517名新生儿和来自耶鲁大学的73名新生儿.
- 在36名耶鲁新生儿的社会注意力评估时,他们的年龄为4.2个月.
- 数据分析涉及比较iFC跨途径,并将其与年龄和社会关注指标相关联.
主要成果:
- 在dHCP队列中,IFC在所有途径中都是积极的,并且与其他途径相比,在正确的社会途径中更高,随着年龄的增长而增加.
- 在耶鲁大学的队列中,新生儿右侧社会途径iFC与4个月的社会关注正相关.
- 4个月时增强的社会注意力预测了生命的第二年更好的社会功能.
结论:
- 在正确的社会感知途径中,内在的功能连接的早期发展是研究的一个关键领域.
- 这种途径的连接性可能提供了对非典型社会注意力背后的神经机制的见解,特别是在自闭症等疾病中.
- 早期的功能连接模式可以作为预测社会发展轨迹的生物标志物.
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