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Updated: May 23, 2025

Visualizing Multiciliated Cells in the Zebrafish Through a Combined Protocol of Whole Mount Fluorescent In Situ Hybridization and Immunofluorescence
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ZEB2信号传递对于尿路平滑肌细胞的分化和维持是必不可少的

Sudhir Kumar1, Xueping Fan1, Harshita Pattam1

  • 1Nephrology Section, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston Medical Center, Boston, Massachusetts, 02118, USA.

bioRxiv : the preprint server for biology
|March 10, 2025
PubMed
概括

莫瓦特-威尔逊综合征 (MWS) 与ZEB2突变有关. 这项研究表明,ZEB2对于尿管正常发育至关重要,因为它缺少会损害光滑肌肉细胞的形成,导致尿路异常.

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Erythropoietin-producing hepatocellular carcinoma receptor (Eph) and its ligand, Eph receptor-interacting protein (Ephrin) were first discovered in the human carcinoma cell line, hence the name. Ephrin-Eph interaction guides cells to reach their appropriate location in adult tissues. They also play an essential role in the immune system by helping in immune cell migration, adhesion, and activation. Based on their structure and function, Eph is divided into two classes — EphA and EphB.
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