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Updated: May 6, 2026

Gramicidin-based Fluorescence Assay; for Determining Small Molecules Potential for Modifying Lipid Bilayer Properties
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Gramicidin-based Fluorescence Assay; for Determining Small Molecules Potential for Modifying Lipid Bilayer Properties

Published on: October 13, 2010

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格拉米西丁D在水中的体分散:制备,表征和差异性细胞毒性

Ricardo Márcio-E-Silva1, Bianca R Bazan1, Rodrigo T Ribeiro1

  • 1Biocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Avenida Professor Lineu Prestes, 748, Butantan, São Paulo, SP 05508-000, Brazil.

ACS omega
|March 10, 2025
PubMed
概括

自组装的Gramicidin D纳米颗粒 (GrNP) 显示出增强的抗菌活性和降低哺乳动物细胞毒性. 这种配方具有治疗感染和癌症的潜力.

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Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations01:15

Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations

Gentamicin, an aminoglycoside antibiotic, is commonly administered via intermittent intravenous infusion to treat severe infections. An intermittent one-hour infusion of gentamicin, administered at eight-hour intervals, allows for precise control of plasma drug concentrations, minimizing toxicity while ensuring therapeutic efficacy. Pharmacokinetic principles govern the dynamics of plasma concentrations and can be mathematically described using specific equations.The plasma drug concentration...
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