试管婴儿/ICSI对甲状腺功能障碍的结果 - 在河内医科大学医院治疗的患者
Nguyen Thanh Hoa1,2, Do Thi Minh Tam1, Nguyen Manh Ha1,2
1Department of Histology and Embryology, Hanoi Medical University, Hanoi, Vietnam.
概括
这项研究发现,虽然治疗过高甲状腺症可能会影响受试管婴儿/ICSI治疗的女性的卵细胞成熟,但它不会影响怀孕率. 在达到安甲状腺状态后,可以恢复生育能力.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 不孕症研究 不孕症研究
- 甲状腺疾病管理管理
背景情况:
- 甲状腺激素显著影响生殖功能,甲状腺功能过高可能导致不孕.
- 虽然安甲状腺恢复可以解决许多症状,但治疗后持续存在的生育问题仍然令人担忧.
研究的目的:
- 评估治疗过度甲状腺症对体外受精/细胞内精子注射 (IVF/ICSI) 结果的影响.
- 为了确定在甲状腺功能障碍治疗后实现了乙甲状腺状态的女性中是否存在生育问题.
主要方法:
- 这是一项回顾性研究,将48对患有治疗过度甲状腺症的不育夫妇 (HT组) 与48对患有卵管堵塞的不育夫妇 (对照组) 进行比较.
- 评估的结果包括试管婴儿周期特征和第一次胚胎移植后的怀孕率.
主要成果:
- 两组之间基线特征 (年龄,不孕症类型,精液质量) 没有显著差异.
- 治疗HT组的BMI较低,并且每个周期成熟卵子细胞减少的趋势.
- 最重要的是,HT组和对照组之间的怀孕率相似.
结论:
- 治疗过高甲状腺症可能会在卵巢刺激期间影响卵细胞成熟,即使在达到安甲状腺状态后也是如此.
- 尽管对卵细胞产量有潜在的影响,但甲状腺功能障碍似乎不会影响IVF/ICSI周期中的怀孕率.
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