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Updated: May 23, 2025

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody
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超越ADCs:利用双特异性抗体直接诱导亡以进行向瘤根除

Victor S Goldmacher1, Iosif M Gershteyn1, Yelena Kovtun1

  • 1Research and Development Department, ImmuVia, Inc., Cambridge, MA 02142, United States.

Antibody therapeutics
|March 10, 2025
PubMed
概括

双特异性亡触发剂 (BAT) 通过激活亡,直接杀死癌细胞,比ADC和BiTE具有潜在的优势. 强大的临床前模型预测了这些新型癌症疗法的临床结果.

关键词:
在TNFRSF10B中.灭症 (apoptosis) 是一种死亡的过程.两种特定抗体的抗体.死亡受体5 死亡受体5有针对性的癌症治疗.

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