从查和健康状况的诊断收益负担的门诊患者有心力衰竭的风险
Omar Cantu-Martinez1,2, Andrew A Girard1,2, Weiwei Jin3,4
1University of Missouri - Kansas City's Healthcare Institute for Innovations in Quality, Kansas City, MO.
medRxiv : the preprint server for health sciences
|March 10, 2025
概括
查心力衰竭 (HF) 风险的初级保健患者,使用非侵入性左心室末腹压 (LVEDP) 确定近40%的患者患有升高的LVEDP. 许多患者表现出严重的健康损害,这表明需要进一步评估HF.
科学领域:
- 心脏病学 心脏病学
- 初级医疗保健医学 一级医疗保健医学
- 诊断查 诊断查 诊断查 诊断查
背景情况:
- 由于非特异性症状和不频繁的查,心力衰竭 (HF) 在初级保健中往往被诊断不足.
- 这导致患者被诊断为晚期疾病,影响他们的生活质量和功能能力.
研究的目的:
- 评估查高风险门诊患者的有效性,使用左心室末端透气压 (LVEDP) 的非侵入性测量.
- 通过这种查方法,鉴定出患有高LVEDP的患者的健康状况.
主要方法:
- 选了患有糖尿病 (DM),慢性病 (CKD) 或怀疑HF的成年人的方便样本.
- 维维奥系统用于非侵入性LVEDP评估,积极查被定义为LVEDP>18 mmHg.
- 使用堪萨斯城心肌病问卷总体总结 (KCCQ-OS) 评分对具有阳性查结果的患者进行健康状况评估.
主要成果:
- 在2040名查患者中,38.5%的LVEDP升高.
- 年龄较大,女性性别和CKD存在与LVEDP升高的可能性较高有关 (p<0.01).
- 在653名KCCQ-OS得分的患者中,31.4%无症状 (KCCQ-OS=100),而26.5%的得分小于80,表明NYHAII-IV类症状.
结论:
- 非侵入性LVEDP查发现了相当一部分高危初级保健患者的LVEDP升高.
- 超过三分之二的阳性查患者报告了显著的健康状况下降.
- 将非侵入性LVEDP评估与KCCQ评分相结合,可以帮助识别可能受益于进一步心力衰竭评估的患者.
相关概念视频
Pathophysiology of Heart Failure
1.4K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.4K
Imaging Studies for Cardiovascular System III: X-Ray
119
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
119
Assessment of the Cardiovascular System I: Subjective Data
257
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
257
Imaging Studies for Cardiovascular System I:Echocardiography
280
Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
280
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
40
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
40
Sensitivity, Specificity, and Predicted Value
157
In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
Sensitivity is the...
157


