在Evolut TAVR中输入到输出支架框架扩展,圆性和脱:对中期血液动力学性能的影响
Rishi Puri1, Julianne Spencer2, Didier Tchétché3
1Heart, Vascular & Thoracic Institute, Cleveland Clinic, Ohio.
概括
评估了跨导管大动脉置换 (TAVR) 框架的圆性和膨胀. 输入不足扩张没有影响4年血液动力学,但叶片区域不足扩张与较小的有效孔径面积有关.
科学领域:
- 心血管成像 - 心血管成像
- 干预心脏病学 干预心脏病学
- 生物医学工程 生物医学工程
背景情况:
- 原生大动脉环表现出可变的圆性,影响过导管大动脉 (TAV) 的性能.
- 非循环和不扩张的TAV可能会影响血液动力学结果.
- 这项研究研究了Evolut TAV框架几何及其临床影响.
研究的目的:
- 量化 演化 TAV 框架圆性和膨胀 30 天 跨导管主动脉置换 (TAVR) 后.
- 评估框架变形对低衰减叶片加厚1年后和血液动力学4年后的影响.
主要方法:
- 从Evolut低风险子研究中对184名患者进行了回顾性分析.
- 计算机断层扫描成像用于量化圆性比率和百分比膨胀.
- 框架变形与临床结果的关联分析.
主要成果:
- 进化的圆度在流入区域是最高的,在叶片和流出区域是最低的.
- 框架扩展在流入区域最低,在传单区域最高.
- 输入框架变形没有影响4年血液动力学;小册子区域不扩张与有效孔面积减少相关.
结论:
- 进化的框架变形在流入时不会影响叶片区域的几何或扩张.
- 中期血液动力学性能 (4年) 不会受到流入框架几何学的不利影响.
- 叶片区域的不扩张是长期TAV功能的一个关键因素.
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