吸烟及其在口腔癌中的作用
Prabhu Manickam Natarajan1, Bhuminathan Swamikannu2, Leela Bhavani3
1Department of Clinical Sciences, College of Dentistry, Centre of Medical and Bio-allied Health Sciences and Research, Ajman University, Ajman, UAE.
Journal of pharmacy & bioallied sciences
|March 10, 2025
概括
吸烟会显著增加口腔癌的风险,因为它会导致遗传突变和炎症. 戒烟对于减少全球口腔癌发病率至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 毒理学 毒理学 毒理学
背景情况:
- 口腔癌是全球主要的健康问题.
- 吸烟是导致口腔癌发展的主要危险因素.
- 烟草烟雾含有许多致癌化合物.
研究的目的:
- 审查吸烟在口腔癌病因学中的作用.
- 为了强调吸烟对致癌的贡献.
- 为了强调戒烟的重要性.
主要方法:
- 流行病学研究的文献综述.
- 对烟草烟雾中致癌化合物的分析.
- 检查致癌的生物机制.
主要成果:
- 吸烟会引发遗传突变,氧化应激,以及口腔组织的炎症.
- 诸如多环芳和亚胺等致癌物转化口腔细胞.
- 在吸烟强度和口腔癌风险之间存在剂量反应关系.
结论:
- 吸烟是导致口腔癌发展的关键因素.
- 戒烟对于减少口腔癌发病率至关重要.
- 公共卫生倡议对于减轻与吸烟相关的口腔癌风险至关重要.
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