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Updated: May 23, 2025

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OATP1B型的运输功能是芳酶抑制剂相关关节痛敏感性的决定因素

Hanieh Taheri1, Yang Li1, Kevin M Huang1

  • 1Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio.

Cancer research communications
|March 10, 2025
PubMed
概括

芳香酶抑制剂 (AIs) 由于药理动力学变异性,可能导致关节疼痛. 肝脏OATP1B转运体影响AI水平,转运体活性降低与乳腺癌患者的AI相关关节痛增加有关.

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