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Rapid In Vivo Assessment of Adjuvant's Cytotoxic T Lymphocytes Generation Capabilities for Vaccine Development
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暂时抑制I型干扰素可以增强CD8+T细胞干细胞和疫苗保护

Benjamin J Broomfield1,2, Chin Wee Tan1,2,3, Raymond Z Qin1,2

  • 1Walter and Eliza Hall Institute of Medical Research , Parkville, Australia.

The Journal of experimental medicine
|March 10, 2025
PubMed
概括

在病毒感染或疫苗接种期间阻断I型干扰素受体 (IFNAR) 会促进长期记忆CD8+T细胞 (TSCM) 的形成. 这一策略增强了疫苗诱导的对慢性感染的保护.

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