在美国查结肠镜检查时结肠直肠腺瘤的种族差异
Yuqi Wu1, Piet C de Groen2, Nabil Natafgi1
1Department of Health Services Policy and Management, University of South Carolina, Columbia, South Carolina.
概括
黑人和白人患者在查结肠镜检查期间具有相似的结肠直肠多形状. 需要进一步的研究,以了解黑人美国人的持续性结肠直肠癌差异.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 健康差异 在健康上的差异
背景情况:
- 黑人美国人的结直肠癌发病率高于白人美国人.
- 尽管自2010年以来的查率类似,但这种差异仍然存在.
- 在查结肠镜检查时结肠直肠腺瘤的状态是癌症风险的关键指标.
研究的目的:
- 为了比较黑人和白人接受查结肠镜检查的患者之间的结肠直肠腺瘤状况.
- 调查腺瘤检测的差异,晚期腺瘤,非晚期腺瘤和超塑性息肉.
- 分析和比较种族群体之间的全息肉负担.
主要方法:
- 使用了查结肠镜检查的横截面观察数据.
- 包括在2001年至2016年期间在南卡罗来纳州进行查的40-89岁的平均风险患者.
- 分析了根据年龄调整的腺瘤和息肉负担的几率,根据性别比较黑人和白人患者.
主要成果:
- 与白人患者相比,黑人患者患腺瘤 (OR=0.88) 和右侧多聚质瘤 (OR=0.74) 的几率较低.
- 种族群体之间在先进的或多个非先进的腺瘤中没有发现显著差异.
- 平均多体负担因年龄和性别而异,黑人男性的负担略高于白人男性,黑人女性的负担略低于白人女性.
结论:
- 黑人和白人患者在一个大规模的,种族平衡的样本中表现出类似的息肉形状.
- 类似的腺瘤状况表明其他因素有助于结直肠癌差异.
- 进一步调查影响多检测的临床因素是有必要的,以解决差异.
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