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Updated: May 23, 2025

Generation of Null Mutants to Elucidate the Role of Bacterial Glycosyltransferases in Bacterial Motility
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Generation of Null Mutants to Elucidate the Role of Bacterial Glycosyltransferases in Bacterial Motility

Published on: March 11, 2022

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电荷很重要:侧面基板如何调节电荷 O-glycan 核心延伸

Collin J Ballard1, Matthew R Smutny1, Lam D Chau1

  • 1Department of Biochemistry, Case Western Reserve University, 2109 Adelbert Rd, Cleveland, OH 44106, United States.

Glycobiology
|March 10, 2025
PubMed
概括

像C1GALT1,B3GNT6和ST6GalNAc-I/-II这样的酶控制O-甘氨酸的延长. 这项研究揭示了它们的基质电荷偏好,影响了糖化和疾病相关性.

关键词:
核心甘氨基转移酶/静电相互作用/GalNAc-T/Golgi/O-glycan延长

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