饮用水管道系统是抗微生物耐药病原体的热点
C Hayward1, K E Ross2, M H Brown3
1Environmental Health, College of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia; Future Industries Institute, University of South Australia, Mawson Lakes, South Australia, Australia.
抗微生物耐药性病原体在住宅饮用水管道中普遍存在,生物膜充当关键储存器. 这突显了迫切需要更好的监测和干预措施来保护公共健康.
科学领域:
- 环境微生物学环境微生物学
- 公共卫生 公共卫生
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 饮用水管道中的抗菌素耐药 (AMR) 病原体对公众健康构成重大风险.
- 管道系统可以容纳多种AMR细菌,增加传播潜力.
研究的目的:
- 调查澳大利亚饮用水和生物膜样本中关键的AMR病原体的流行情况,包括耐甲黄金葡萄球菌 (MRSA) 和耐卡巴胺的Pseudomonas aeruginosa和Acinetobacter baumannii.
- 为了在医院和住宅的管道系统中识别AMR病原体的储存库.
主要方法:
- 利用定量聚合酶连锁反应 (qPCR) 和基于培养的方法来检测病原体.
- 从澳大利亚各地的住宅和医院管道装置中取样饮用水和生物膜.
主要成果:
- 73%的住房样本对至少一个AMR病原体呈qPCR阳性,而医院样本的比例为38%.
- 排水生物膜被确定为AMR的主要储库 A. baumannii,S. aureus和P. aeruginosa.
- 检测到相当大比例的耐卡巴胺的P. aeruginosa (29%) 和A. baumannii (28%),以及MRSA (54%).
结论:
- 管道生物膜是各种抗抗药性病原体的关键热点,增加了弱势群体的风险,特别是在家庭医疗保健中.
- 迫切需要加强监测和有针对性的干预措施,以减轻饮用水管道系统中的AMR风险.
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