抗菌素抗性肠球菌 (VRE) - 在新加坡的一家三级医院出现流行病
Indumathi Venkatachalam1, May Kyawt Aung2, Deborah Chooi Mun Lai3
1Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore; Department of Infectious Diseases, Singapore General Hospital, Singapore.
The Journal of hospital infection
|March 10, 2025
概括
在新加坡综合医院,抗菌素耐药性肠球菌 (VRE) 仍然是流行病,其获得与MRSA或CPE等共感染以及特定药物使用有关. 有针对性的预防和管理是减少VRE感染的关键.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 临床微生物学 临床微生物学
背景情况:
- 抗胺素抗性肠球菌 (VRE) 构成了医疗保健方面的重大挑战.
- 了解VRE流行病学和风险因素对于有效控制至关重要.
研究的目的:
- 描述从2018年到2023年变化的VRE流行病学.
- 在第三级医院中识别VRE获得和感染的风险关联.
主要方法:
- 从2018年至2023年对住院VRE数据的回顾性审查.
- 对风险因素的发病趋势分析和病例控制研究.
- 环境查VRE的存在.
主要成果:
- 确诊的VRE病例超过5000例,主要是E. faecium与vanA.
- 与医疗保健相关的VRE感染和细菌病的稳定率.
- 获得VRE的重要风险因素包括MRSA/CPE同时携带,ICU入院,血液透析,手术和万科胺/美特罗尼达使用.
结论:
- VRE是流行病,对患者和环境造成了巨大的负担.
- 同时感染和特定的抗菌药物使用是VRE获取的关键驱动因素.
- 有针对性的感染预防和抗菌药物管理可以减轻VRE感染.
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