在青春期,前前的网络经历了功能专业化,后面是腹脊梯度:发育轨迹和纵向关联
Samuel D Klein1, Paul F Collins1, Vanessa Lozano-Wun1
1University of Minnesota-Twin Cities Department of Psychology, Elliot Hall, 75 E River Road, Minneapolis, MN.
概括
青少年大脑发育显示了奖励和执行功能网络的明显变化. 腹部条纹连接与奖励区域加强,而背部条纹连接与执行功能区域加强,支持改进决策.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 认知神经科学 认知神经科学
背景情况:
- 前前的电路整合了奖励处理和认知控制.
- 青少年的冒险行为可能源于这些电路中的成熟失衡.
- 双重神经系统理论假设不同的奖励和执行系统的发展.
研究的目的:
- 调查腹部 (VS) 和背部 (DS) 带状静止连接 (rsFC) 的发展轨迹.
- 检查这种发展是否与青少年发育的双神经系统理论一致.
- 将网络发展与奖励处理和执行功能的变化联系起来.
主要方法:
- 从11至25岁的163名参与者的长度静止状态fMRI扫描.
- 数据收集在四个评估浪潮多年.
- 分析腹部和背部状RSFC发育及其与行为改善的相关性.
主要成果:
- 与奖励相关的区域 (例如,带状皮质) 的VS rsFC增加,与执行功能区域 (例如,前额叶皮质) 的VS rsFC减少.
- DS rsFC显示了相反的模式,随着执行职能领域的增加.
- 更快的VS rsFC发展与更好的奖励决策相关;DS rsFC发展与更好的执行功能相关.
结论:
- 青少年神经发育的特征是腹部和背部前前连接的分歧.
- 这些变化支持情感决策和执行功能的发展改进.
- 非典型的前腹状网络发展可能是青少年精神病理学的基础.
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