生活必需8和糖尿病病之间的关联:基于人口的研究
Cong Liu1, Jiju Yang2, Hongdian Li1
1Department of Nephrology, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing, China.
通过Life's essential 8 (LE8) 测量较高的心血管健康得分,与糖尿病患者患糖尿病病 (DKD) 的风险降低有关. 这项研究表明,LE8可能有助于评估DKD风险.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 糖尿病患者面临心血管和脏疾病的高风险.
- 生活必需8 (LE8) 是心血管健康 (CVH) 的新指数.
- LE8可以帮助评估糖尿病病 (DKD) 风险.
研究的目的:
- 在糖尿病患者中探索LE8和DKD之间的关系.
- 为管理DKD的临床策略提供证据.
- 评估LE8亚尺度与DKD风险的关联.
主要方法:
- 分析了来自NHANES的3715名参与者,代表1890万美国居民.
- 以混因素进行调整,以确定与LE8分数相关的DKD风险.
- 使用受限立方线回归来分析LE8-DKD关系.
主要成果:
- 在糖尿病患者中发现了36.39%的加权DKD患病率.
- 较高的LE8分数与较低的DKD风险显著相关 (或0.54为中度,或0.18为高).
- 在LE8得分和DKD风险之间观察到线性关系.
结论:
- 较高的LE8得分与发展DKD的风险降低有关.
- LE8及其子尺度显示了作为DKD风险评估工具的潜力.
- 需要进一步的前性研究来证实长期的因果关系.
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