预测代谢-腹部手术后的第一年怀孕:机器学习模型的开发和验证
Raheleh Moradi1, Maryam Kashanian2, Fahime Yarigholi3
1Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran. raheleh.moradi1987@gmail.com.
Surgical endoscopy
|March 11, 2025
概括
机器学习模型可以在代谢 - 腹部手术 (MBS) 后12个月内预测怀孕. 这有助于管理受MBS治疗的生殖年龄妇女的生殖健康.
科学领域:
- 生殖健康 生殖健康
- 腹部外科手术的结果
- 机器学习在医学中的应用
背景情况:
- 代谢 - 减肥手术 (MBS) 是一个关键的减肥干预,许多患者是生殖年龄的女性.
- 在怀孕之前,建议在MBS后进行12个月的间隔,以优化结果.
- 预测MBS后的早期怀孕对于生殖健康服务评估至关重要.
研究的目的:
- 开发和验证机器学习 (ML) 模型,用于在MBS后的第一年内预测怀孕.
- 确定影响MBS后怀孕时间的关键因素.
主要方法:
- 一项嵌套病例控制研究,涉及473名MBS后怀孕的妇女 (2009-2023年).
- 应用各种ML算法,包括分类,决策树 (C5.0) 和回归分析.
- 在MBS的12个月内确定怀孕的诱导因素.
主要成果:
- C5.0决策树模型实现了0.920 ± 0.014的AUC,证明了高预测准确度.
- 该模型确定了13个早期怀孕的显著预测因素,包括月经不规则,婚姻状况,BMI,PCOS和T2DM.
- 灵敏度和特异性分别为0.762 ± 0.044和0.916 ± 0.028. 这两种特异性分别为0.762 ± 0.044和0.916 ± 0.028.
结论:
- ML模型可以有效地预测MBS后12个月内怀孕.
- 这些预测工具可以帮助减肥外科医生和产科医生管理患者护理.
- 改进的预测有助于预防低于最佳的外科反应和不良妊娠结果.
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