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Updated: May 23, 2025

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罕见的致病性结构变体显示出增强非洲男性前列腺癌生殖基因检测的潜力

Tingting Gong1,2, Jue Jiang1, Korawich Uthayopas1

  • 1Ancestry and Health Genomics Laboratory, Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, 2050, Australia.

Nature communications
|March 11, 2025
PubMed
概括

前列腺癌 (PCa) 的结构变异 (SVs) 不成比例地影响了非洲血统. 这项研究确定了15种致病性SV,强调了在测试指南中需要包含性基因组数据的必要性.

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