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Updated: May 23, 2025

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy
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Published on: May 4, 2016

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在调节线粒的过程中,SMAD3和PINK1之间存在正反循环

Mingzhu Tang1, Dade Rong1, Xiangzheng Gao1

  • 1Faculty of Healthy Sciences, Ministry of Education Frontiers Science Center for Precision Oncology, University of Macau, Macau, China.

Cell discovery
|March 11, 2025
PubMed
概括

SMAD家族成员3 (SMAD3) 激活PTEN诱导的激酶-1 (PINK1) 转录,独立于TGFβ信号传递. 这创造了一个积极的反循环,对于线粒体压力期间的线粒体衰变和细胞存活至关重要.

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