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Updated: May 23, 2025

Investigation of Protein Recruitment to DNA Lesions Using 405 Nm Laser Micro-irradiation
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Published on: March 20, 2018

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DNA病变经常会在DNA:RNA混合积累之前发生

Raphaël M Mangione1, Steven Pierce2, Myriam Zheng1,2

  • 1Université Paris Cité, CNRS, Institut Jacques Monod, Paris, France.

Nature communications
|March 11, 2025
PubMed
概括

DNA:RNA杂交物可以在DNA损伤后积累,但这些"损伤后"杂交物不会加剧遗传不稳定性或基因表达问题. 这一发现与"损伤前"杂交物形成鲜明对比,为DNA修复机制提供了新的见解.

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