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Updated: Jul 3, 2026

Generation of Microtumors Using 3D Human Biogel Culture System and Patient-derived Glioblastoma Cells for Kinomic Profiling and Drug Response Testing
09:24

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探索患者特定的体外管道,用于对基于微质细胞的治疗药物的分层和药物反应预测

Carla Cuní-López1,2, Romal Stewart3,4, Satomi Okano5

  • 1Brain and Mental Health, QIMR Berghofer Medical Research Institute, 300 Herston Rd, Herston, QLD, 4006, Australia. c.cunilopez@uqconnect.edu.au.

Scientific reports
|March 11, 2025
PubMed
概括

开发针对阿尔茨海默病 (AD) 的个性化药物需要更好的生物标志物. 这项研究引入了一个新的管道,使用类似微质细胞来识别患者亚组,并预测神经退行性疾病的治疗反应.

关键词:
在体外2D和3D模型.我们的MDMi MDMi单细胞衍生的微质细胞.患者的分层是患者的分层.临床前药物测试 临床前药物测试预测的临床前管道.

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Author Spotlight: Induced Microglia-Like Cell Technology to Shed Light on the Role of Microglial Dysfunction in Neuropsychiatric Disorders06:12

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