从1990年到2021年,骨关节炎负担和不平等:对全球疾病负担的系统分析 2021年研究研究
Ruofeng Wu1, Yu Guo2, Yi Chen3
1Department of Operation, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
Scientific reports
|March 11, 2025
概括
骨关节炎 (OA) 的发病率和残疾在1990-2021年期间在全球范围内急剧增加. 高BMI,女性性别和区域差异推动了这种不断增长的健康负担,要求有针对性的干预措施.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 类风湿病学 类风湿病学
背景情况:
- 骨关节炎 (OA) 是一个重大的全球健康挑战,导致广泛的残疾.
- 了解OA不断变化的趋势和促成因素对于有效的公共卫生战略至关重要.
研究的目的:
- 分析从1990年到2021年的全球OA发病率,残疾生活年数 (YLDs) 和年龄标准化率 (ASIR/ASYR).
- 调查人口统计,地区和社会人口统计指数 (SDI) 五分位数的开放式教育趋势和决定因素.
主要方法:
- 利用的全球疾病负担 (GBD) 研究2021年数据.
- 雇佣的joinpoint回归,年龄周期队列 (APC) 建模,分解和不平等分析.
- 根据性别,地区和SDI五分位数的研究趋势.
主要成果:
- 全球OA发病率从2090万病例上升至4660万病例;YLD从892万病例上升至2130万病例.
- 在高SDI国家观察到更高的OA率,女性受到的影响不成比例.
- 亚洲地区的ASYR增长最快;高BMI是一个重要的贡献者,特别是在高SDI的国家.
结论:
- 全球OA负担不断升级,需要立即关注和有针对性的干预措施.
- 解决肥胖等可修改的风险因素,以及早期检测和管理至关重要.
- 缓解性别和社会经济差异对于有效的OA预防和控制至关重要.
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