巴林老年患者的潜在不合适药物:患病率,预测因素和对实践的影响
Mohamed Fadhel Abdulla1, Fawaz Eyad Obaid2, Osama Sobhi Moaket1
1School of Medicine, RCSI Medical University of Bahrain, Busaiteen, Kingdom of Bahrain.
BMC geriatrics
|March 11, 2025
概括
巴林初级保健中超过一半的老年人使用潜在不合适的药物 (PIM). 女性性别,糖尿病和年龄是关键的风险因素,突出了老年人药物治疗中有针对性的干预措施的必要性.
科学领域:
- 老年人药物疗法药物疗法
- 公共卫生 公共卫生
- 药物的安全性 药物的安全性
背景情况:
- 全球老年人口的增长需要了解药物管理.
- 可能不合适的药物 (PIMs) 带来风险:药物不良反应,住院治疗和医疗费用增加.
- 这项研究针对巴林老年成人初级保健患者的PIM患病率和风险因素.
研究的目的:
- 确定巴林初级医疗保健中心的老年人中PIM使用的流行率.
- 在这个人口群体中确定与PIM使用相关的风险因素.
- 为改善老龄人口中药物安全的干预措施提供信息.
主要方法:
- 在2022年在巴林27个初级医疗保健中心进行的横截面研究.
- 包括65岁及以上的患者,采样使用基于计算机的简单随机方法.
- 通过2023年的Beers标准评估药物适当性;通过单变量和逻辑回归分析数据.
主要成果:
- 在595名老年人中,51.3%的老年人至少接受了一次PIM.
- 格利克拉齐德,潘托普拉和拉贝普拉是最常见的PIMs.
- 在女性和患有糖尿病,高血压和高脂血症的患者中,PIM的使用率更高. 年龄,女性性别和糖尿病是重要的预测因素 (分别为OR=1.09,1.645,1.696).
结论:
- 巴林超过一半的老年成人患者使用PIM,这表明公共卫生问题很重要.
- 迫切需要针对女性,糖尿病患者和多药店患者进行有针对性的干预.
- 研究结果支持制定政策,以优化老年人群中药物安全.
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