尿液白细胞计数用于区分无症状细菌尿和尿路感染,并预测二次细菌血症
Yongseop Lee1, JongHoon Hyun2, Je Eun Song2
1Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Journal of Korean medical science
|March 11, 2025
概括
尿液白细胞计数有助于区分尿路感染 (UTI) 和无症状细菌性尿病 (ASB),特别是在非沟通患者中. 较高的发烧症表明细菌病风险增加,但死亡率没有增加.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 临床诊断 临床诊断 临床诊断
背景情况:
- 在有沟通困难的患者中,区分无症状细菌尿 (ASB) 和尿路感染 (UTI) 是一个挑战.
- 准确的诊断对于适当的治疗和患者的结果至关重要.
研究的目的:
- 评估尿白细胞在区分尿路感染和ASB的诊断准确度.
- 根据尿路感染水平评估尿路感染患者的临床结果.
主要方法:
- 具有阳性尿液培养的患者的回顾性队列研究 (2022年7月 - 2023年6月).
- 基于综合医疗记录审查的尿路感染和ASB的诊断.
- 尿液白细胞计数的分析和与临床结果的相关性.
主要成果:
- 与ASB (123.5细胞/μL) 相比,患有尿路感染的患者尿液白细胞数量 (490.4细胞/μL) 显著增加.
- 尿白细胞的诊断性能中等 (AUC 0.702),最佳切线为195.35细胞/μL.
- 炎症增加与上部尿路感染病例中二次细菌病的更高率相关,但与住院死亡率无关.
结论:
- 尿白细胞计数可以帮助预测尿路感染和相关细菌病,特别是在患有模糊症状的患者中.
- 较高的炎症水平与细菌病风险有关,但不能预测死亡率.
- 白细胞计数为管理细菌性尿症提供了有价值的补充数据.
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