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Updated: May 23, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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在骨髓移植后的乳腺癌中通过基于组织的基因组测试成功检测BRCA2突变:对精准医学的影响

Chisato Takeuchi1, Seiichi Imanishi1, Namiko Tanaka1

  • 1Department of Breast Surgery, Osaka Rosai Hospital, Osaka, JPN.

Cureus
|March 11, 2025
PubMed
概括

生殖系BRCA1/2突变查对于遗传性乳腺癌至关重要. 基于组织的测试可以在骨髓移植后的患者中识别可操作的突变,当血液测试不可行时.

关键词:
骨髓移植 骨髓移植腕部分析 腕部分析在brca1/2突变中.parp 抑制剂的使用基于组织的基因小组测试.

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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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