通过调节FXR-NLRP3介导的巨细胞亡,缓解大肠炎

Lijiao Yang1, Wanyu Li1, Qianjing Zhao1

  • 1Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, National Key Clinical Specialty, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, 300052, People's Republic of China.

概括

萨卡罗米切斯布拉迪超 (SbS) 通过激活FXR和抑制NLRP3炎症酶来缓解性结肠炎 (UC),从而减少巨细胞的烧灭. 这种益生菌干预为炎症性肠病 (IBD) 提供了一种新的治疗策略.

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