对COVID波的临床比较 2-5 . 巴基斯坦卡拉奇的一位住院患者的回顾性比较分析
Muneeba Ahsan Sayeed1, Elisha Shalim2, Shaiza Farman2
1Infectious Diseases Department, Sindh Infectious Diseases Hospital & Research Center, Dow University of Health Sciences, Karachi, Pakistan.
Open forum infectious diseases
|March 11, 2025
概括
COVID-19 2-5 波显示出独特的临床模式. 与三角洲变种相关的第4波在住院患者中呈现了最高的疾病严重程度和死亡率.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 临界护理医学 临界护理医学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 波表现出不同的临床表现和结果.
- 了解这些变异对于有效的患者管理至关重要.
研究的目的:
- 为了比较COVID-19的临床特征和结果,在住院患者的环境中,波数从2到5.
- 识别每个波的独特特征及其对患者预后的影响.
主要方法:
- 对3190名入院的成年患者进行了回顾性研究,这些患者在COVID-19聚合酶连锁反应测试中呈阳性.
- 数据收集于2020年7月至2022年3月,在辛德省传染病医院和研究中心.
- 使用SPSS 26进行的统计分析.
主要成果:
- 第二波的排放率最高 (81%),死亡率最低 (18.9%).
- 波3显示了细胞因子释放综合征的最高发病率 (32.7%).
- 第4波 (三角洲变种) 呈现最严重的严重程度:79.4%的严重COVID,27.1%的输管,24.3%的败血症休克,50.8%的疾病进展,以及最高的死亡率 (42.5%).
- 第五波主要影响的是老年人 (平均年龄68岁),患有轻度疾病 (22.4%),高并发症 (84.6%) 和严重急性损伤 (29.2%).
结论:
- 每个COVID-19浪潮都表现出独特的临床特征和患者结果.
- 波4,由三角洲变种驱动,是最严重和最致命的,与其他波相比,死亡率明显更高.
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