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Updated: May 23, 2025

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肠道电流测量检测了直肠表皮中CFTR功能的年龄相关差异.

Simon Y Graeber1,2,3, Olaf Sommerburg4,5, Yin Yu4,5

  • 1Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität, Berlin, Germany.

Frontiers in pharmacology
|March 11, 2025
PubMed
概括

囊性纤维化转膜导电调节器 (CFTR) 在直肠上皮的功能随着年龄的增长而下降,可能是由于分泌结肠细胞的减少. 这种与年龄相关的下降可能解释了为什么儿童对CFTR调节器疗法比成年人更有反应.

关键词:
在CFTR中,CFTR是最重要的.在CFTR调节器疗法中使用CFTR调节器.年龄依赖性 年龄依赖性肠道电流测量测量这是直肠表皮质的直肠表皮.分泌性腹 腹 的情况.

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