概括
剩余胆固醇 (RC) 水平因性别和年龄而异,与传统的胆固醇模式不同. 通过这些因素对RC管理进行分层是有效预防心血管疾病的关键.
科学领域:
- 心血管医学 心血管医学
- 临床化学 临床化学
- 公共卫生 公共卫生
背景情况:
- 动脉样硬化心血管疾病 (ASCVD) 是一个全球性的健康威胁,与异常的脂质代谢作为一个关键的风险因素.
- 与残留胆固醇 (RC) 相关的残留风险是一个新兴的研究领域.
- 关于RC在不同性别和年龄组的分布的数据有限.
研究的目的:
- 为了研究残留胆固醇 (RC) 与性别和年龄相关的分布.
- 为了比较RC分布与传统的脂质样本 (TC,HDL-C,LDL-C).
主要方法:
- 利用了20265名2022年9月至2023年3月期间收集的实验室数据.
- 测量TC,HDL-C和LDL-C;使用样本公式计算RC.
- 使用SPSS分析了RC的性别和年龄特定分布和差异.
主要成果:
- 总胆固醇,LDL-C和非HDL-C在男性 (31-40岁) 中的峰值比女性 (51-60岁) 早.
- 在年轻女性 (21-40岁) 和年长男性 (71-90岁) 中观察到较低的RC度.
- 在性别和年龄组之间发现了RC分布的显著差异.
结论:
- 剩余胆固醇的分布模式不同于传统的胆固醇指标.
- 建议根据性别和年龄量身定制残留胆固醇管理策略,以改善心血管风险降低.
相关概念视频
Cholesterol: Significance and Regulation
492
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
492
Blood Studies for Cardiovascular System III: Serum Lipid Profile
115
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
115
Lipids: Dietary Sources and Requirements
646
Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ...
646
Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
Lipid-derived Compounds in the Human Body
4.3K
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
4.3K
Oogenesis
63.3K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.3K


